The C1019T Polymorphism in Connexin 37 and Helicobacter pylori in Patients with Gastric Cancer

The gap junctional protein (Durlej et al., 2011; Xu, et al., 2012; Shaker et al., 2012) ( connexin, Cx ) are present in the cells that is responsible to exchange information and substance, which was channel protein and was essential for cell proliferation, differentiation and body growth and development of Cx. The Cx function is complex, in many physiological and pathological processes are involved, more meaningful, it is correlated with tumor development (Finegold et al., 2012), known as “the second kind of tumor suppressor gene”. And Cx is a multigene family, all members of the gene sequence have a high degree of homology. At present, it had 13 sorts in human tissue,